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1、單擊此處編輯母版標(biāo)題樣式,單擊此處編輯母版文本樣式,第二級,第三級,第四級,第五級,*,*,Bronchial asthma,Department of respiration,Kong lingfei,Bronchial asthma,1,Asthma i human killer/,Asthma i human killer/,2,Background of asthma,Prevalence in the world: 1.6 hundred million,in China:1-3,in Shenyang: 1.24 %(1999),GINA: Global Initiative fo
2、r Asthma (1994,WHO /HLBI,Bronchial asthmatic diagnosis guideline( 1997,Chinese medical academy,Background of asthma,3,Definitions of asthma,Chronic airway inflammation,Broncho-hyperresponsiveness BHR,Airflow limitation,Definitions of asthma,4,Mechanism: allergy theory,antigen,antigen,atopy IgE antib
3、ody mast cells., basophils,histamine,inflammatory mediaLTs,PAF,ECP,immediate asthmatic reaction, IAR,bronchial smooth muscle spasm,airway narrow,Mechanism: allergy theory,5,Mechanism: never-receptor disorder theory,adrenergic and cholinergic nerous systems, AC,non-adrenergic and non-cholinergic nero
4、us systems, NANC,AC: al-receptor, MI, M3-receptors ) excitement,NANC: PS-receptor,bronchial smooth muscle contraction,AC: receptor、 M2-receptor,excitement,NANC: VIP receptor,bronchial smooth muscle dilation,asthmatic airway:al、M1、M3、PS/、M2、VP,Mechanism: never-receptor diso,6,Mechanism: airway inflam
5、mation theory,antigen,allergic airway inflammation AAI,ECP,MBP,inflammatory cells inflammatory mediaLTs,EOS,PAF,neutrophils,late asthmatic reaction. LAR,Tlymphocyte(Thi/Th2D),Th2 cytokine Il3、4、5, GM-CSFlgE,Mechanism: airway inflammation,7,Differ mechanisms in acute and chronic asthma,acute,chronic,
6、inflammation,inflammation,remodelling,bronchial contraction,inflammation cells,cell proliferation,mucous edema,epithelium injury,airway secretion,excellular base,aIrway,aIrway narrow,BHR,reversibility,symptoms,exacerbation,Differ mechanisms in acute and,8,Other mechanisms: induced factors,Allergen:
7、pollen, acarus,infection: virus or mycoplasmal infection,climate and physical and chemical factors,drugs: aspirin induced asthma, AIA,- receptor inhibitor,heredity,Gastroesophageal reflux disease GERD,Psychological, incretion factors, sports,Other mechanisms: induced fact,9,Diagnosis standards of as
8、thma,symptoms,signs,recovered ways,except other cardiac and pulmonary diseases,lung function examination untypical asthma,Diagnosis standards of asthma,10,支氣管哮喘英文版課件,11,支氣管哮喘英文版課件,12,支氣管哮喘英文版課件,13,支氣管哮喘英文版課件,14,支氣管哮喘英文版課件,15,支氣管哮喘英文版課件,16,支氣管哮喘英文版課件,17,支氣管哮喘英文版課件,18,支氣管哮喘英文版課件,19,支氣管哮喘英文版課件,20,支氣管哮喘英文版課件,21,支氣管哮喘英文版課件,22,支氣管哮喘英文版課件,23,支氣管哮喘英文版課件,24,支氣管哮喘英文版課件,25,支氣管哮喘英文版課件,26,支氣管哮喘英文版課件,27,支氣管哮喘英文版課件,28,支氣管哮喘英文版課件,29,支氣管哮喘英文版課件,30,支氣管哮喘英文版課件,31,支氣管哮喘英文版課件,32,支氣管哮喘英文版課件,33,支氣管哮喘英文版課件,34,支氣管哮喘英文版課件,35,支氣管哮喘英文版課件,36,支氣管哮喘英文版課件,37,支氣管哮喘英文版課件,38,支氣管哮喘英文版課件,39,支氣管哮喘英文版課件,40,支氣管哮喘英文版課件,41,
支氣管哮喘英文版課件
